The placental problem: Linking abnormal cytotrophoblast differentiation to the maternal symptoms of preeclampsia
Abstract The placenta is a remarkable organ.In normal pregnancy its specialized cells (termed cytotrophoblasts) differentiate into various specialized subpopulations Chillums that play pivotal roles in governing fetal growth and development.One cytotrophoblast subset acquires tumor-like properties that allow the cells to invade the decidua and myom